Full Schedule
| Matchup | Week | Date/Time | Spread | Total | Result |
|---|---|---|---|---|---|
| ATLvs Atlanta Falcons | 1 | Sun, Sep 13, 12:00 PM | PIT -6.5 -3.5 | 40.5 -2 | W 20–13 |
| NEat New England Patriots | 2 | Sun, Sep 20, 12:00 PM | PIT +5.5 -1 | 41.5 -2 | L 3–20 |
| CINvs Cincinnati Bengals | 3 | Sun, Sep 27, 12:00 PM | PIT +3.5 +2 | 42.5 -4 | W 30–27 |
| CLEat Cleveland Browns | 4 | Thu, Oct 1, 7:15 PM | PIT -2.5 | 38.5 -2 | L 24–27 |
| INDvs Indianapolis Colts | 5 | Sun, Oct 11, 12:00 PM | PIT -3 -0.5 | 41.5 -6 | W 34–22 |
| TBat Tampa Bay Buccaneers | 6 | Sun, Oct 18, 12:00 PM | PIT -1.5 +3 | 38.5 -7 | W 26–19 |
| NOat New Orleans Saints | 7 | Sun, Oct 25, 8:30 AM | PIT -3 +0.5 | 43.5 +1 | W 16–10 |
| CLEvs Cleveland Browns | 8 | Sun, Nov 1, 12:00 PM | PIT -3.5 +2.5 | 38.5 -1 | W 27–6 |
| CINat Cincinnati Bengals | 10 | Sun, Nov 15, 7:20 PM | — | — | — |
| PHIat Philadelphia Eagles | 11 | Sun, Nov 22, 3:25 PM | — | — | — |
| DENvs Denver Broncos | 12 | Fri, Nov 27, 2:00 PM | — | — | — |
| HOUvs Houston Texans | 13 | Sun, Dec 6, 7:20 PM | — | — | — |
| JAXat Jacksonville Jaguars | 14 | Mon, Dec 14, 7:15 PM | — | — | — |
| BALvs Baltimore Ravens | 15 | Sun, Dec 20, 12:00 PM | — | — | — |
| CARvs Carolina Panthers | 16 | Sat, Dec 26, 11:00 PM | — | — | — |
| TENat Tennessee Titans | 17 | Sun, Jan 3, 12:00 PM | — | — | — |
| BALat Baltimore Ravens | 18 | Sat, Jan 9, 11:00 PM | — | — | — |
Division
The Steelers play in the AFC North, which means six of their games every season come against these three clubs.