Full Schedule
| Matchup | Week | Date/Time | Spread | Total | Result |
|---|---|---|---|---|---|
| JAXat Jacksonville Jaguars | 1 | Sun, Sep 13, 12:00 PM | CLE +8.5 -1 | 40.5 | L 10–34 |
| TBat Tampa Bay Buccaneers | 2 | Sun, Sep 20, 12:00 PM | CLE +7.5 -2 | 41.5 -1 | — |
| CARvs Carolina Panthers | 3 | Sun, Sep 27, 12:00 PM | CLE +2.5 +1 | 40.5 +1 | — |
| PITvs Pittsburgh Steelers | 4 | Thu, Oct 1, 7:15 PM | CLE +2.5 | 40.5 | — |
| NYJat New York Jets | 5 | Sun, Oct 11, 12:00 PM | CLE +1.5 +1 | 39.5 | — |
| BALvs Baltimore Ravens | 6 | Sun, Oct 18, 12:00 PM | CLE +6.5 | 44.5 | — |
| TENat Tennessee Titans | 7 | Sun, Oct 25, 12:00 PM | CLE +2.5 | 40.5 | — |
| PITat Pittsburgh Steelers | 8 | Sun, Nov 1, 12:00 PM | CLE +6 | 39.5 | — |
| NOat New Orleans Saints | 9 | Sun, Nov 8, 12:00 PM | CLE +3.5 | 41.5 | — |
| HOUvs Houston Texans | 10 | Sun, Nov 15, 12:00 PM | CLE +4.5 | 38.5 | — |
| LVvs Las Vegas Raiders | 12 | Sun, Nov 29, 12:00 PM | CLE -1.5 | 39.5 | — |
| CINvs Cincinnati Bengals | 13 | Sun, Dec 6, 12:00 PM | CLE +4.5 | 45.5 | — |
| ATLvs Atlanta Falcons | 14 | Sun, Dec 13, 12:00 PM | CLE -1.5 | 40.5 | — |
| NYGat New York Giants | 15 | Sun, Dec 20, 12:00 PM | CLE +4.5 | 40.5 | — |
| BALat Baltimore Ravens | 16 | Sun, Dec 27, 12:00 PM | CLE +10 | 43.5 | — |
| INDvs Indianapolis Colts | 17 | Sun, Jan 3, 12:00 PM | CLE +2.5 | 43.5 | — |
| CINat Cincinnati Bengals | 18 | Sat, Jan 9, 11:00 PM | CLE +7.5 | 43.5 | — |
Division
The Browns play in the AFC North, which means six of their games every season come against these three clubs.