Full Schedule
| Matchup | Week | Date/Time | Spread | Total | Result |
|---|---|---|---|---|---|
| SFvs San Francisco 49ers | 1 | Thu, Sep 10, 7:35 PM | LAR -3.5 | 47.5 -1 | L 7–27 |
| NYGvs New York Giants | 2 | Mon, Sep 21, 7:15 PM | LAR -6.5 +2 | 47.5 -1 | W 28–6 |
| DENat Denver Broncos | 3 | Sun, Sep 27, 7:20 PM | LAR -1.5 -1.5 | 43.5 -2 | L 26–30 |
| PHIat Philadelphia Eagles | 4 | Sun, Oct 4, 12:00 PM | LAR -3.5 +2 | 42.5 -5 | W 24–20 |
| BUFvs Buffalo Bills | 5 | Mon, Oct 12, 7:15 PM | LAR -3.5 -0.5 | 55.5 +2 | L 34–37 |
| ARIvs Arizona Cardinals | 6 | Sun, Oct 18, 3:05 PM | LAR -12.5 +1 | 51.5 +4 | L 16–18 |
| LVat Las Vegas Raiders | 7 | Sun, Oct 25, 3:25 PM | LAR -3.5 -4 | 49.5 +3 | W 35–21 |
| LACvs Los Angeles Chargers | 8 | Sun, Nov 1, 3:05 PM | LAR -6.5 -3 | 46.5 -2 | W 24–9 |
| WASat Washington Commanders | 9 | Sun, Nov 8, 12:00 PM | LAR -5.5 | 47.5 -3 | — |
| ARIat Arizona Cardinals | 10 | Sun, Nov 15, 3:05 PM | LAR -7.5 -3 | 47.5 | — |
| GBvs Green Bay Packers | 12 | Wed, Nov 25, 7:00 PM | — | — | — |
| KCvs Kansas City Chiefs | 13 | Thu, Dec 3, 7:15 PM | — +1 | — | — |
| SFat San Francisco 49ers | 14 | Sun, Dec 13, 3:25 PM | — | — | — |
| DALvs Dallas Cowboys | 15 | Sun, Dec 20, 3:25 PM | — | — | — |
| SEAat Seattle Seahawks | 16 | Fri, Dec 25, 7:15 PM | — | — | — |
| TBat Tampa Bay Buccaneers | 17 | Sat, Jan 2, 11:00 PM | — | — | — |
| SEAvs Seattle Seahawks | 18 | Sat, Jan 9, 11:00 PM | — | — | — |
Division
The Rams play in the NFC West, which means six of their games every season come against these three clubs.